(now archaic or literary) certainly, yes (indeed), but of course (used to contradict a negative assertion)

(Quebec, informal) So, therefore, in that case

what's done is done; it's no use crying over spilt milk

we all live in hope

(law) violence / (Canada, Quebec) assault, battery

state of affairs, real situation, factual situation, inescapable fact

social reality, social phenomenon

(linguistics) linguistic feature characteristic of a given language (and worthy of some in-depth analysis)

because of, on account of, due to

nothing works! it's hopeless! it's no use!