first, foremost, number one

(anatomy) a secondary sex characteristic

(informal, men's speech) an interrogative particle / (dated) a particle used to state something with conviction

世代: age, generation

代理人: agent

代弁: paying, acting by proxy, or acting for another / 大便: feces

陽大: a male given name

大刀: long sword

大文, 大紋: a type of 直垂 (hitatare) clothing with a family or clan coat of arms displayed prominently / 大門: a large gate; a family of high social standing / 代紋: a yakuza coat of arms

懈怠: spiritual sloth; laziness