Minamiko is my best friend.

Makiko is my best friend.

Kanako is my best friend.

Mieko is my best friend.

A unary operator operates on one operand.

This disease is caused by the gene.

In this math problem, it is important to correctly understand the operand.

He achieved results in the exam that were in accordance with his reputation.

He succeeded in a difficult project with the spirit of 'ishi no ue ni mo sannen', which means great works are performed by perseverance.

His effort is exactly like the proverb 'Even a fool can move a mountain.'