classical adnominal stative of 病む (yamu, “to fall ill”): has fallen ill, is sick

(transitive) to vex, to annoy, to cause distress, to make someone suffer / (intransitive, rare) to be vexed, to be bothered about something, to be distressed about something

the adnominal or attributive form of stative / resultative 悩めり (nayameri, “has been vexed”)

a classic

意味: a meaning, a significance, the point / 異味: strange or different flavor

a meaning; a significance; a point / meaning; definition

to mean, signify, imply

to say, to tell somebody / to call, to name, to give a name / to cry, to call, to make a noise (such as an animal)

past tense and perfective aspect of 言う (iu, yū) [godan]

nonetheless, although, be that as it may