To become unsteady.

(UK) To lose courage and determination. / Used other than figuratively or idiomatically: see lose, bottle.

(Ireland, colloquial, figuratively) get carried away; lose one's self-control; exceed one's limits or limitations

To become disoriented.

To stop doing or fail to do something because one lacks courage.

To find oneself unable to speak; to be able to come up with nothing to say.

(informal, euphemistic, figuratively) To throw up; vomit.

Third-person singular simple present indicative form of lose one's rag

Third-person singular simple present indicative form of lose one's shit

Third-person singular simple present indicative form of lose one's virginity