(idiomatic) To begin or launch; to get going.

(Ireland, idiomatic) eventually, despite all the confusion.

(pharmacology) A drug sold during the late 1950s and early 1960s as a sleeping aid, and to pregnant women as an antiemetic to combat morning sickness and other symptoms, but withdrawn as causing severe birth defects, such as phocomelia; currently used to treat leprosy.

(mildly vulgar, slang) An intensive form of what. / (mildly vulgar, slang) Indicating acceptance, indulgence, or insouciance: Why not? Who cares?

(idiomatic) Not informed, up-to-date, or current; not included in a process or discussion.

(idiomatic) To make an extra effort; to do a particularly good job.

(sequence, idiomatic) to begin with; earlier; firstly; originally; at the start, / (idiomatic) at all, even (typically in non-negated statements)

(idiomatic) In the focus of attention, especially from the media.

(idiomatic, humorous, euphemistic) To be homosexual.

(informal, usually with a negative) To know, understand or have a clue.