(informal) To damage; to treat harshly; to produce ill effects in.

It is better to be patient than impatient.

(vulgar, idiomatic) To urinate profusely, especially in reference to a profound need to do so.

Too much focus on one's career may lead to one being uninteresting company. / Too much hard work and not enough leisure time can be unhealthy.

(idiomatic) To encounter an unexpected problem or delay.

A unique specimen.

(slang) To be insane, irrational, or eccentric.

A sure thing is preferable to the mere chance at something more.

(simile, colloquial) Stark naked; nude; especially, naked in a public setting and without embarrassment.

(idiomatic) To terminate or abolish something.