a protein forming membrane-bound complexes with CD11s, its lack causing leukocyte adhesion deficiency, and also occurring in a soluble form which plasma levels are inversely correlated with disease activity in spondyloarthritis.

(biochemistry) The α (alpha) component of various integrins, especially ones in which the β (beta) component is CD18 (i.e. β2) and which mediate leukocyte adhesion.

the alpha protein subunit that forms with CD18 the heterodimeric integrin macrophage-1 antigen (Mac-1) also known as complement receptor 3 (CR3), present on the surface of many leukocytes involved in the innate immune system

a peptide of 12 amino acids, associated with certain types of lymphoma and targeted by alemtuzumab.

a cell membrane protein of the tumor necrosis factor receptor family, serving as a tumor marker and the target of brentuximab vedotin

a cell surface protein that is used as a marker of plasma cells, targeted by elotuzumab.

a glycoprotein expressed on the surface of T, B, natural killer and dendritic cells; its extracellular domain is a receptor for the measles virus.

a membrane protein acting as an inhibitory complement receptor, being port-of-access for measles, human herpesvirus-6 and Neisseria.

(biochemistry) B-cell and FDC membrane protein involved in the complement system and B cell coreceptor complex, and bound by EBV.

a protein that constitutes the Knops blood group system; it processes and clears complement opsonized immune complexes