(idiomatic, Britain) in a tight spot.

Unequivocally and intransigently opposed to.

(idiomatic) In a very difficult position.

(now rare) To be unfavourable to; to work against.

(idiomatic) To be disadvantageous to someone.

(figuratively) To discover or find something by accident. / (figuratively) To meet somebody by chance.

To think less of (someone) for (something they have done).

(transitive, idiomatic) To function as a liability (for someone); to put into a condition of disadvantage. / (transitive, idiomatic) To serve as evidence which casts doubt upon.

(rare, nonstandard) Alternative form of dead against.

To violate; to breach; to break. / To be unfavourable to someone. / To be contrary to a trend, feeling or principle. / To oppose; to resist