(chiefly US) To perform a mathematical calculation.

(informal) To damage; to treat harshly; to produce ill effects in.

(UK, colloquial) To go away, to leave; to get lost.

The cardinal number occurring after do and before do two in a duodecimal system. Written 11, decimal value 13.

A list of errands and other tasks – often written on a piece of paper as a memory aid – that one needs or intends to accomplish.

(informal) I cannot do it.

Alternative form of do the honors

(idiomatic) To act as a host to guests. / (idiomatic) To perform a duty.

(idiomatic) To abuse an illegal drug or drugs, especially as a result of chemical addiction.

(informal) confident and willing to get a job done.