(followed by a phrase) Regardless, in spite of. / (not followed by a phrase) Regardless of any or most possible adverse circumstances.

Someone or something that has no hope of success.

(computing) An instruction or operation that has no effect; a null operation.

(LGBT, of a transgender or transsexual person) Having chosen not to undergo sex reassignment surgery.

(LGBT) A transgender or transsexual person who has chosen not to undergo sex reassignment surgery.

(music) A broad musical and artistic movement originating in the mid-1970s in New York City, typified by experimentation and performance art.

One feels most comfortable at home.

Used to cut off objections or qualifications.

Alternative form of hobnob

Alternative form of hobnob