To quit, to stop engaging in a line of work or type of activity.

(colloquial, dated) To pay for oneself, not relying on the generosity of others.

(informal) to think very hard about.

Third-person singular simple present indicative form of hang up one's spurs

(rare) Misconstruction of risk life and limb

(informal) to work very hard.

(UK) Synonym of sweat one's guts out

Synonym of sweat one's guts out

Synonym of sweat one's guts out

Synonym of sweat one's guts out