He took upon himself the responsibility of organizing the event.

He takes it upon himself to fix the broken window.

She is taking upon herself the responsibility of organizing the event.

He decided to take upon himself the responsibility of organizing the event.

I will take it upon myself to finish the project.

She always crosses herself before entering the church.

She makes something of herself by starting her own business.

She is making something of herself by starting her own business.

He made something of himself by starting his own business.

He is skilled at playing the guitar with his onehanded technique.