(chiefly Britain, slang) Someone or something very annoying.

generalized pains in the limbs or joints of children or adolescents (from many causes) / emotional or social problems associated with adolescence

(medicine, pathology) A sensation of pain coming from a part of the body that has been amputated, or in which the nerves have been destroyed.

(law) A species of damages that one may recover for physical or mental pain that results from a wrong done. / Used other than figuratively or idiomatically: see pain, suffering.

The minimum intensity or duration of a sensory stimulus applied to a living being at which it becomes considered painful.

plural of pain in the ass

(medicine) Pain caused by damage to nerves or by damage to the brain, brainstem, or spinal cord.

A painful bottom as a result of riding a mount or vehicle with (or without) a saddle

plural of pain killer

Alternative spelling of painkiller