(video games) Initialism of Super Smash Bros. for 3DS.

(video games) Initialism of Super Smash Bros. Ultimate.

(video games) (collective) Super Smash Bros. for Wii U and Super Smash Bros. for 3DS.

(computing) Initialism of Streaming SIMD Extensions 2, an extension to the x86 CPU instruction set architecture building off the earlier SSE and intended to completely replace the older MMX and 3DNow! extensions.

plural of SSaDV

plural of SSAE

Initialism of same-sex attraction disorder. (a now-discredited diagnosis of homosexuality in the field of psychiatry)