A rare genetic disorder characterized by short stature, brachycephaly, and other facial abnormalities; hand defects, including brachydactyly; and distinctive ocular abnormalities.

A rare congenital bleeding disorder caused by a reduction or absence of alpha-granules in blood platelets, and the release of proteins normally contained in these granules into the marrow, resulting in myelofibrosis.

A genetic disorder characterised by fine sparse scalp hair, thin nails, a pear-shaped broad nose, and cone-shaped epiphyses of the middle phalanges of some fingers and toes.

A rapid and severe brain swelling caused by a second concussion before a first has sufficiently healed, such as may occur after suffering two concussions during the same sports match. It has catastrophic results and may cause death or permanent disability.

plural of second impact syndrome

A rare disease characterized by the congenital fusion of any two of the seven cervical vertebrae.

a variety of behavioral and medical disturbances, including irritability, depression, insomnia and irritable bowel syndrome, polar T3 syndrome, Antarctic stare

A rare genetic disorder causing various bodily malformations.

A rare genetic disorder characterized by an abnormally shaped skull, short stature, and aplasia or hypoplasia of the radius bone in the forearm.

A rare, sometimes fatal congenital disorder featuring abnormal development of the pancreas, nose, and scalp, with mental retardation, hearing loss, and growth failure.