(colloquial) What is that? / (colloquial) What was that?

Alternative form of that's what's up (“that's true”) / (slang) This is excellent; this is cool. Used to express approval

(literally) Interested in that; having such a tendency. / (specifically, euphemistic) Gay, homosexual.

Alternative form of God helps those who help themselves

(economics) The economic policies followed by Margaret Thatcher, British prime minister.

however

(idiomatic, almost always preceded by the) The person who stimulates or inspires a group; the major factor affecting a trend or set of developments.

Alternative form of the hand that rocks the cradle rules the world

Women, particularly mothers, have a decisive influence on the future direction of society because they raise and nurture the next generation.

Alternative form of it's an ill wind that blows nobody any good