indicates the importance of persistence in the pursuit of success.

Only those who are faultless have the right to pass judgment upon others (implying that no one is faultless and that, therefore, no one has such a right to pass judgment).

Alternative form of let him who is without sin cast the first stone

When finding oneself in a troubling situation, one should first make sure one is not making the situation worse by his own actions before addressing all other causes.

Synonym of if you find yourself in a hole, the first thing to do is stop digging

(formal) In the first place; before anything else; first.

The first child to be born to a parent or family.

Born as the first one in a family, flock or the like. / Most excellent; most distinguished or exalted.

Direct, without intermediate stages. / Not previously owned or used; contrasted with secondhand.

The first produce or result, notably firstborn offspring. / The first of a class or kind. / The thing first thought or done.