He has gone west to pursue his dreams.

She has gone hard on her training.

She has gone downtown to do some shopping.

He has gone far in his career.

He traveled to hell and gone to find the lost treasure.

She has gone nowhere in her career despite her efforts.

He has gone to the mattresses to protect his family.

He has gone mad with power.

He has gone to the scaffold.

My grandfather has gone aloft.