A troublesome state of affairs.

Asks the age of the interlocutor. / (impolite) Used to question the mental age (maturity) of the interlocutor.

(China, humorous) Why is it always you? You again?

Alternative form of that's the way the cookie crumbles.

(slang, Britain) A whatsit; a thing which the speaker is unable or unwilling to specify more precisely. / (slang, Britain, euphemistic) Sexual intercourse.

(informal) Alternative form of how do you do

(Australia) An informational card or leaflet published by a political party and distributed to the general public, usually near voting booths during election time, to indicate how to vote for a particular party.

plural of how-to-vote card

(humorous, rhetorical question) Asked to tall people or someone that is at a high vantage point, either literally or metaphorically.

(colloquial, manner) In any way or manner, without particularly caring which is chosen; anyhow.