In terms of, or by means of, the bodily fluids or humours.

(uncountable) A subgenre of comedy and satire that deals with subjects that are believed to be serious or controversial, such as death, divorce, drug abuse, etc.

(American spelling, idiomatic) Comedy that still manages to be funny in the face of, and in response to, a tragic or hopeless situation.

US standard spelling of sense of humour.

(ophthalmology, US) The clear gel that fills the eyeball between the lens and the retina.

(immunology) Immunity to infection due to antibodies, which circulate in the blood and lymph, and which are produced by B cells.

Happy, cheerful, amiable.

Alternative spelling of ill humor

Having a bad temper. / Irritable in a surly manner.

bad temper / irritability or surliness