(medicine, archaic) A pea, or similar round body, used to maintain irritation in a wound, and promote the secretion and discharge of pus.

(law) An issue produced in a pretended action between two parties for the purpose of trying before a jury a question of fact which it becomes necessary to settle in the progress of a cause.

plural of issuing

A village in Aosta Valley, in northwestern Italy.

Initialism of International Standard Serial Number.

A member of the first generation of Japanese immigrants to North America, South America, or Australia.

plural of issei

Lynx issiodorensis, an extinct lynx that inhabited Europe during the Pleistocene epoch.

The state, condition, or quality of being an issue or problem.

plural of non-issue