Third-person singular simple present indicative form of lose control

(set phrase) To become unable to control one's emotions or actions; to abandon rationality or reason.

(slang) To become angry.

(figuratively) To be killed, usually in a gruesome manner. / (literally) To suffer decapitation.

(idiomatic) To lose all of one's money; to go broke; to undergo financial ruin or disaster.

To have sexual intercourse for the first time.

(slang) To vomit, throw up.

(intransitive, idiomatic) To become angry or annoyed.

(idiomatic) To become frustrated, angry. / (idiomatic) To become crazy, insane.

(idiomatic) To lose one's special mastery of or knack for a particular skill or activity.