That makes a difference; that is consequentially important.

(rare) The act of making a difference.

To do (something) reasonably successfully.

To act in a friendly or conciliatory way.

(hypnotism) To perform a hypnotic technique involving running the hands over the head and body of the subject.

(idiomatic) To attempt to escape; to flee; to run away. / (idiomatic) To run so as to avoid being late.

To talk with someone out of courtesy, to pass time, or in an effort to engage with them socially.

To unambiguously indicate interest in sexual activity to someone the speaker has not previously been sexually involved with.

Alternative form of makepeace

plural of make-debate