(US, idiomatic) To exert effective effort; to get going; to get moving; to start producing.

(chiefly US, informal) From any perspective; in every case.

Alternative form of set one's heart on

(idiomatic, UK) Not to allow oneself to be set back, daunted, upset or embarrassed by unpleasant or undesirable circumstances.

To insist, demand, or refuse with finality. / (informal, literally) To make a vehicle go faster; accelerate.

(idiomatic, rare) To sit down.

To come to an accounting; to examine and strike the balance of debt and credit; reckon. / (idiomatic, archaic) To vomit.

(transitive, idiomatic) to leave alone, unsupervised, without assistance.

(idiomatic) To be busy or thoroughly preoccupied.

Used other than figuratively or idiomatically: see off, top, head. / (idiomatic) In an extemporaneous manner; without careful thought, preparation, or investigation.