(idiomatic) To tell an obvious untruth.

(idiomatic) Hurt or destroyed by one's own plot or device intended for another; "blown up by one's own bomb".

(idiomatic) To open an office or business, especially in a profession.

(idiomatic) To relax.

(idiomatic) To reform; to improve one's habits.

(US, idiomatic) To exert effective effort; to get going; to get moving; to start producing.

(chiefly US, informal) From any perspective; in every case.

Alternative form of set one's heart on

(idiomatic, UK) Not to allow oneself to be set back, daunted, upset or embarrassed by unpleasant or undesirable circumstances.

To insist, demand, or refuse with finality. / (informal, literally) To make a vehicle go faster; accelerate.