(physiology) A sensory area in the skin that responds to a decrease in temperature.

plural of cold spot

(idiomatic) A sentimental fondness or affection. / A point of vulnerability in a defence. / A fontanelle.

A location of difficulties or hostilities; a hot spot; a flashpoint.

(chemistry) The addition of a single drop of a reagent to a small sample as a qualitative analytical test for the presence of a specific compound or class of compounds.

A dark brown blemish on the skin, usually caused by exposure to the sun.

plural of liver spot

A birthmark, especially on a woman. / A place noted for its natural beauty. / (historical, cosmetics) A patch or spot placed on the face in order to heighten beauty by contrast.

(pathology) any of various diseases causing fever and spots on the skin

(ice hockey) One of the five spots in an ice hockey rink where play may begin.