(transitive) To make (a person) angry, distressed, or unhappy. / (transitive) To disturb, disrupt or adversely alter (something). / (transitive) To tip or overturn (something).

The highest or uppermost side or portion of something. / A favourable aspect of something that also has an unfavourable aspect. / (finance) An upward tendency, especially in a financial market etc.

(informal) On the top of.

Living or situated remote from the seacoast

The interior of the country.

Towards the interior of the country and away from the seacoast.

(transitive) To end up; to set on end. / To tip or turn over. / (figuratively) To destroy, invalidate, overthrow, or defeat. / To affect or upset drastically.

Located on a higher floor or level of a building. / (baseball, informal) Pertaining to a pitched ball that is high, and usually outside the strike zone.

Up the stairs; on a higher floor or level. / (informal) In the brain or mind. / (informal) In heaven, especially with regard to where a deity might be found.

An upper storey. / (slang, euphemistic) A woman's breasts.