(US) The semi-official use of a drug that has not yet gained official approval in cases where no other treatment is possible

To treat someone badly, cruelly or unkindly.

Bad, cruel or unkind treatment.

simple past tense and past participle of use up

Worn out; depleted; exhausted; having nothing left; useless, due to the expenditure of all resources.

plural of US American

Used other than figuratively or idiomatically: see let, us. / Alternative form of let's

(software engineering) A potential scenario in which a system receives an external request (such as user input) and responds to it.

Frequently used.

(US) A charge imposed on the use or possession of personal property