To face a large task or project.

Too much focus on one's career may lead to one being uninteresting company. / Too much hard work and not enough leisure time can be unhealthy.

(US, military, idiomatic, sometimes humorous) Used by senior enlisted military personnel to indicate that they are not commissioned officers.

Synonym of the road to hell is paved with good intentions

(archaic) second-person singular simple past form of work