最終更新日：2024/07/31
(pharmacology) A protein drug that binds to and blocks the action of tumor necrosis factor and is administered by injection to treat various inflammatory diseases (such as rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis). It is a dimeric protein consisting of the ligand-binding portion of a human receptor for tumor necrosis factor linked to the basal, heavy chain, portion of IgG which determines the immune response to bound antigen. It is produced by recombinant DNA technology using hamster ovary cells and is marketed under the trademark Enbrel.
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etanercept
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元となった辞書の項目
etanercept
noun
(pharmacology)
A
protein
drug
that
binds
to
and
blocks
the
action
of
tumor
necrosis
factor
and
is
administered
by
injection
to
treat
various
inflammatory
diseases
(such
as
rheumatoid
arthritis,
psoriatic
arthritis,
and
ankylosing
spondylitis).
It
is
a
dimeric
protein
consisting
of
the
ligand-binding
portion
of
a
human
receptor
for
tumor
necrosis
factor
linked
to
the
basal,
heavy
chain,
portion
of
IgG
which
determines
the
immune
response
to
bound
antigen.
It
is
produced
by
recombinant
DNA
technology
using
hamster
ovary
cells
and
is
marketed
under
the
trademark
Enbrel.
意味（1）
(pharmacology)
A
protein
drug
that
binds
to
and
blocks
the
action
of
tumor
necrosis
factor
and
is
administered
by
injection
to
treat
various
inflammatory
diseases
(such
as
rheumatoid
arthritis,
psoriatic
arthritis,
and
ankylosing
spondylitis).
It
is
a
dimeric
protein
consisting
of
the
ligand-binding
portion
of
a
human
receptor
for
tumor
necrosis
factor
linked
to
the
basal,
heavy
chain,
portion
of
IgG
which
determines
the
immune
response
to
bound
antigen.
It
is
produced
by
recombinant
DNA
technology
using
hamster
ovary
cells
and
is
marketed
under
the
trademark
Enbrel.
