agony, pain / distress, torment, anguish

薬品: medicine

(slang, feminine speech) saddening

suffix used by female given names, such as 奈美 (なみ, Nami), 恵美 (えみ, Emi; めぐみ, Megumi), 宏美 (ひろみ, Hiromi) / (rare) suffix used by male given names