(transitive) To twist something, to hold something from both ends and turn it in opposite directions; to wring, to pirl, to screw. / (transitive) To castrate. / (transitive) To give the mouth an acrid or bitter taste, or a puckering or drying sensation, such as after eating an unripe persimmon or a quince. / (intransitive) (of stomach, of bowels) To hurt, to twinge, to gripe. / (transitive) To hurt, to injure.