The state of having invested heavily in just one area. / The state of having devoted all of one’s resources to one thing.

(transitive, obsolete) To lead away. / (transitive, obsolete) To lead; conduct.

(US, historical) A postal delivery route by means other than railroad or steamboat.

(organic chemistry) Any of a group of anthraquinone derivatives, present in Micromonospora lupini, that inhibit tumour growth