最終更新日:2022/12/24
Although the ovaries are the main source of androgen excess in PCOS, excess adrenal androgen (AA) levels (e.g., dehydroepiandrosterone [DHEA] and adrenal-secreted androsteredione [A4]) and adrenocortical dysfunction have also been observed in many patients with PCOS (2–6). Proof of the role of AA excess in the development of PCOS is circumstantial at best.
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Although
the
ovaries
are
the
main
source
of
androgen
excess
in
PCOS,
excess
adrenal
androgen
(AA)
levels
(e.g.,
dehydroepiandrosterone
[DHEA]
and
adrenal-secreted
androsteredione
[A4])
and
adrenocortical
dysfunction
have
also
been
observed
in
many
patients
with
PCOS
(2–6).
Proof
of
the
role
of
AA
excess
in
the
development
of
PCOS
is
circumstantial
at
best.