Absence or dysfunction of GPIb-V-IX results in the Bernard-Soulier Syndrome, a bleeding disorder characterised not only by impaired platelet adhesion, but also by macrothrombocytopenia, due to a disturbed link between the GPIb-V-IX complex and the underlying cytoskeleton during platelet and/or MK formation [17 ].

For here forlorn and loſt I tread, / With fainting ſteps and ſlow; / Where wilds immeaſurably ſpread, / Seem lengthening as I go.

He may sometimes exaggerate the truth for the sake of the expression, sometimes perhaps sacrifice it; but he never degenerates into mere phrasemongery.

Without the help of vellicles, hooks, or grappers.