We represent pk-structures as orientable fatgraphs, which naturally leads to a filtration by their topological genus.

Of particular relevance to the ICU [intensive care unit] setting is ketorolac, a NSAID [non-steroidal anti-inflammatory drug] that is being increasingly used for pain control in order to avoid problems of respiratory depression, sedation, and addiction associated with narcotics. […] ICU patients, who typically are under great stress from an acute illness that is often accompanied by multiorgan dysfunction including renal insufficiency, are especially prone to develop renal complications from ketorolac[…].

Sneezing, masticatories, and nasals are generally received.

Similarly, antonymic relationships vary by sense.