The slow saturation of the animal economy by the metal renders the individual saturnine, and prepares in him a fresh ground, containing a reserve of lead, which, under the influence of accidental causes, may pass back in a notable quantity into the blood and bring on accidents analogous to those of acute poisoning or presenting special characteristics. The first effects of lead impregnation are, production of saturnine anæmia … acute or chronic saturnine asthma then come on; …