But by your leaves, my learned foes / Ye're maybe wrang

Little Sea and Desire, blessed, nerveless savages, were sound asleep.

In such instances, a biopolishing step following ISCO could be advantageous to remove residual contaminants and ensure complete remediation.

And even the like precurse of fierce events, As harbingers preceding still the fates And prologue to the omen coming on, Have heaven and earth together demonstrated Unto our climatures and countrymen. (Shakespeare)