Among genetic lipodystrophies, the fat loss is observed either since birth as in congenital generalized lipodystrophy, or it occurs later in life as in familial partial lipodystrophy.

From these supposed neolithic origins, the cult had declined with the advent of Christianity into a clandestine folk way practiced and handed down by a handful of individuals since medieval times, especially on the Welsh Marches, the place of its supposed prehistoric origin.

Tar spot is a relatively minor disease in the Americas, but it is very common and often is present on 50% of the leaves in a grove.

Therefore the aim was to correlate the clinical, functional and histopathological staging and to analyze the polarization colors and thickness of the collagen fibers in different stages of OSMF using picrosirius red stain under polarizing microscopy so as to assess the severity of disease.