The C-terminal portion of the variegin chain exits the active site, binds at the “prime” subsites and continues along the thrombin surface to exosite I.

Finally, we mention that several papers studied nonlinear eigenvalue problems of the form -𝛥x(z)=𝜆f(x(z)) fora.a.z∈𝛺,\x|_(∂𝛺),x>0 for scriptstyle 𝜆>0 under the assumption that scriptstyle f: ℝ→ ℝ is continuous, positive, monotone. For this reason such problems were named positone... If the nonlinearity scriptstyle f: ℝ→ ℝ is continuous, monotone and scriptstyle f(0)<0,...then the eigenvalue problem is called semipositone...

This 22-ha area protects a fragment of granitic soil that nurtures a host of species, most striking of which are bulb-like plants such as the multi-hued babianas and lachenalias; white, read and pink sundews (carnivorous plants that meet their mineral needs by feeding on insects); the 'evening flowers', or aandblomme, whose heady scent fills the air at dusk, and the lovely chincherinchees, creamy blooms that grow profusely in the area.

In Niaux, claviforms played a special role in that respect because we also find them very far inside the cave near the end of the galleries. … The same structure is visible at the Salon Noir itself. There, a claviform and a parallel bar were made on the first panel to the right, at the entrance.