最終更新日:2022/12/24
A less advanced class of compounds is the steroidal sulphamoylated compounds; the lead compound, 2-methoxyoestradiol-3,17- O,O - bis -sulphamate, is still in pre-clinical development but has shown potent anti-cancer activities both in vitro and in vivo ( Chander et al, 2007 ; Raobaikady et al, 2005 ; Newman et al, 2008 ; Day et al, 2009 ; Meyer-Losic et al, 2013 ).
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A
less
advanced
class
of
compounds
is
the
steroidal
sulphamoylated
compounds;
the
lead
compound,
2-methoxyoestradiol-3,17-
O,O
-
bis
-sulphamate,
is
still
in
pre-clinical
development
but
has
shown
potent
anti-cancer
activities
both
in
vitro
and
in
vivo
(
Chander
et
al,
2007
;
Raobaikady
et
al,
2005
;
Newman
et
al,
2008
;
Day
et
al,
2009
;
Meyer-Losic
et
al,
2013
).