最終更新日：2022/12/24
Since CS-6253 represents a safe and drugable compound, we investigated its anti-atherogenic effects on different stages of RCT, including ABCA1 interactions, HDL assembly and subsequent HDL remodeling events in human plasma CS-6253 is a close analog of ATI-5261, with substitutions of aromatic phenylalanine for aliphatic leucine residues and has a superior safety profile.
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Since
CS-6253
represents
a
safe
and
drugable
compound,
we
investigated
its
anti-atherogenic
effects
on
different
stages
of
RCT,
including
ABCA1
interactions,
HDL
assembly
and
subsequent
HDL
remodeling
events
in
human
plasma
CS-6253
is
a
close
analog
of
ATI-5261,
with
substitutions
of
aromatic
phenylalanine
for
aliphatic
leucine
residues
and
has
a
superior
safety
profile.
