最終更新日:2022/12/24
Consistent with the role of SLC22A1 in the uptake of the styrylpyridinium dye ASP, K562OCT1 cells showed higher ASP incorporation compared to K562S, while silencing of SLC22A1 or treatment with the specific SLC22A1 inhibitor amantadine (Ama) [ 18 ] led to decreased ASP incorporation levels similar to K562S.
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Consistent
with
the
role
of
SLC22A1
in
the
uptake
of
the
styrylpyridinium
dye
ASP,
K562OCT1
cells
showed
higher
ASP
incorporation
compared
to
K562S,
while
silencing
of
SLC22A1
or
treatment
with
the
specific
SLC22A1
inhibitor
amantadine
(Ama)
[
18
]
led
to
decreased
ASP
incorporation
levels
similar
to
K562S.