最終更新日:2022/12/23
MTX is actively accumulated in the liver where it is metabolized and stored in polyglutamated form, thus decreases folate levels by the inhibition of dihydrofolate reductase[5].
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MTX is actively accumulated in the liver where it is metabolized and stored in polyglutamated form, thus decreases folate levels by the inhibition of dihydrofolate reductase[5].