最終更新日：2022/12/24
Due to topological differences from conventional c ircular c ovalently c losed (CCC) plasmid DNA vectors, the linear topology of LCC DNA ministrings may present differences with regards to DNA interaction and the physicochemical properties influencing DNA-surfactant interactions in the formulation of lipoplexed particles.
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Due
to
topological
differences
from
conventional
c
ircular
c
ovalently
c
losed
(CCC)
plasmid
DNA
vectors,
the
linear
topology
of
LCC
DNA
ministrings
may
present
differences
with
regards
to
DNA
interaction
and
the
physicochemical
properties
influencing
DNA-surfactant
interactions
in
the
formulation
of
lipoplexed
particles.
