It is everywhere observed that a liberated slave is apt to make a merciless master, and that boys who have been cruelly fagged at school are cruel faggers.

[…] pray you, if you know, Where in the purlieus of this forest stands A sheep-cote fenc’d about with olive trees?

It participates in the regulation of SCF complex deactivation by the deneddylation of cullin.

It is associated with neuroinflammation-related events that participate in pain generation and chronicization.