The opiate antagonist naloxone blocks both stimulation-produced analgesia from brain stimulation and analgesia from stimulation of acupuncture points, thus suggesting that a descending pain system able to inhibit pain perception can be associated with the endorphinergic pathway in the brain and spinal cord.

I know ther are many intelligent gentlemen in this age, and great antiquitaries, that questiones the truth of severall particulars contained in the historie of the Douglasses, as though that author, to magnifie above all measure these of whom he writes, doeth obscure, or, at the least, minches the reputatione of others, particularly in this action, as in severall others that occurred, in the tymes of these memories he writes off.

The Avalanche’s raison d’être is theoretically its midgate —— the rear wall of the cab, behind the second-row seats —— which can be lowered to extend the 63-inch-long bed by another 34 inches inside the cab (displacing back-seat passengers in the process).

A quantitative analysis of this behavior and of all our experimental observations is fully consistent with mono and bilayer MoTe₂ being direct band-gap semiconductors, with tetralayer MoTe₂ being an indirect gap semiconductor, and with trilayers having nearly identical direct and indirect gaps.This conclusion is different from the one reached for other recently investigated semiconducting transition metal dichalcogenides, for which only monolayers are found to be direct band-gap semiconductors, with thicker layers having indirect band gaps that are significantly smaller, by hundreds of meV, than the direct gap.