最終更新日：2022/12/24
As seen in Fig 8, SB-206553 exhibits a binding mode in the α7 nAChR-ECD where the amino group of the carbamate establishes a hydrogen bond with the carbonyl group of Asp133, whereas the pyrroloindole moiety appears located between Phe151 and Phe155, a position that would favor π-stacking interactions between the corresponding aromatic rings.
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元となった例文
As
seen
in
Fig
8,
SB-206553
exhibits
a
binding
mode
in
the
α7
nAChR-ECD
where
the
amino
group
of
the
carbamate
establishes
a
hydrogen
bond
with
the
carbonyl
group
of
Asp133,
whereas
the
pyrroloindole
moiety
appears
located
between
Phe151
and
Phe155,
a
position
that
would
favor
π-stacking
interactions
between
the
corresponding
aromatic
rings.
