最終更新日:2022/12/24
However, mutants csg2 Δ (Csg2 is required for mannosylation of inositol phosphorylceramide (IPC)), sur1 Δ (Sur1 encodes the Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit) and cka2 Δ (Cka2 is involved in phosphorylation of ceramide synthase), although also involved in the synthesis of complex sphingolipids, did show levels of GS activity similar to that of the wild-type strain (Fig. 6 ).
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However,
mutants
csg2
Δ
(Csg2
is
required
for
mannosylation
of
inositol
phosphorylceramide
(IPC)),
sur1
Δ
(Sur1
encodes
the
Mannosylinositol
phosphorylceramide
(MIPC)
synthase
catalytic
subunit)
and
cka2
Δ
(Cka2
is
involved
in
phosphorylation
of
ceramide
synthase),
although
also
involved
in
the
synthesis
of
complex
sphingolipids,
did
show
levels
of
GS
activity
similar
to
that
of
the
wild-type
strain
(Fig.
6
).